• The authors define a 'medical reversal' as when a new study--better powered, controlled, or designed than its predecessors--contradicts current practice.  Between 2001 and 2010 they found 363 articles in the NEJM that evaluated a current established medical practice against previous practice.   Overall, 146 (40%) of the studies were reversals, the current practice was either not...
  • It's tempting to think after seven years of a stewardship program that the lessons have been learned and provider behavior will not go back to the bad old days.  Or at least that it won't take such a focused effort to maintain the improved prescribing and the savings that come with it.  This is a...
  • What this really interesting study shows is that not many C. difficile infections appear to be traceable to other known cases.  In this study of all cases in Oxfordshire County in Great Britain, about 1/6th of new cases were plausibly linked to previous cases in a healthcare or community setting, and another 1/6th were genetically...
  • The case definition for Ventilator Associated Pneumonia (VAP) has been too complex to automate and has enough subjective elements in the definition to make comparisons of rates across institutions potentially unfair.  This proposal by CDC's working group on the topic is a big step in the right direction, especially as the first two tiers of...